Personal statement (uni application) Example | Topics and Well Written Essays - 500 words

(uni application) - Personal Statement Example The combinations of these elements in a design give it distinctiveness. Interior design seeks to reflect the esthetic value of things in the environment. Personally think there is more to interior design than acquiring the perfect art piece or choosing the most color palette. It requires skill and precision in understanding a clients design needs. The work of an interior designer should ultimately give any space purpose and tasteful value. Interior design is human-centered. It requires consultation with both the client and the architect to have a clear understanding of the intended space for designing. Additionally, there is more to interior design than making spaces attractive. The interior designer adds functional value and creates efficiency and safety to an area to improve the quality of the working and living milieu. Ensuring harmony with the principles of design amounts to the success of interior design. The principles of interior design are unity, balance, proportion, emphasis, similarity, contrast, and hierarchy. Balance ensures equilibrium in a design that may be symmetrical or asymmetrical. Primarily, any design plan ought to have unity in all its elements. The interior designer must create a design by referring to the most vital parts first in a hierarchal process. Scale emphasizes on the size of the items in question. A focal point should always dominate the design with both contrast and magnitude. Fusing similarity and contrast give an allure of life and excitement to a design. In summary, the reason I like interior design, is that from my childhood days, I have always loved designs in rooms and the functional value that it adds to a chamber. I am passionate about designing rooms so that they become more appropriate for the purpose. I need to augment my skills and add more knowledge in the topic as I pursue a career in interior design. Interior design is intrinsic and has a lifetime upshot on the lives of everyone in

Impacts of MIS on Aramex Assignment Example | Topics and Well Written Essays - 2000 words

Impacts of MIS on Aramex - Assignment Example As the paper discusses  while MIS reduces the occurrence of human error, it does not eliminate error. Managers will have to train and educate the employees on the various impacts MIS has on the entire organization’s operations, especially if they are to achieve competitive advantage. For Aramex, the way MIS is implemented will determine whether IT will drive business or whether MIS will become a function to be absorbed by business lines as managers become more versed with the systems. Because MIS will determine the future strategic direction for Aramex it is important to determine the impact of MIS on Aramex’s decision-making, organizational structure, data security, as well as the impact that future trends are likely to have on Aramex’s strategy.  This study outlines that  Aramex has an abundance of data at their disposal that they can draw on when making decisions. Aramex can use many tools in the analysis of data to improve on their decision-making.  A ramex are able to bring a vast collection of analytical tools to focus efforts and extract data value in adding value to the organization. Aramex uses MIS in decision making as MIS provides a process through which Aramex can transform data, which is dispersed or disorganized into high quality information with added value that allows Aramex to make decisions that are more effective.  MIS also has the ability to increase the employee’s insights on the information.... h which Aramex can transform data, which is dispersed or disorganized into high quality information with added value that allows Aramex to make decisions that are more effective (Edwards et al, 2000, p. 37). MIS also provides for a process that coherently combines skills to analyze and interpret information from numerous organizational sources, as well as the ability to aid non-specialists in deciphering complex technical information. Finally, MIS also has the ability to increase the employee’s insights on the information (Edwards et al, 2000: p38). MIS aids in the process of value extraction from data, such as the development of a hypothesis, data gathering, data analysis, data interpretation, communication of insights, and making decisions that are informed to take action (Fazlollahi & Vahidov, 2001, p. 236). MIS has the ability to move an organization to effective handling of information from simply working with data, turning it into knowledge with added value for competiti ve advantage. At Aramex, their MIS framework compares to the Plan Do Check Act cycle (personal communication, August 1, 2013), which is an almost modern quality control. This was designed by Dr. Edwards Deming, which he also referred to as the Shewhart cycle. In six sigma programs, Dr. Deming further refined this cycle in to; define, measure, analyze, control, and improve cycle (Fazlollahi & Vahidov, 2001, p. 236). Using information to enhance decision-making has to do with data conversion into information, while the information is further converted into knowledge that can help the organization in making decisions (Wiederhold, 2000: p89). According to Mr. Kamal, Aramex uses the PPVC system for data conversion (personal communication, August 1, 2013). PPVC as a prescriptive normative model

Neural Grafts for PD Symptoms

Neural Grafts for PD Symptoms New Neurons for Old The Swedish neuroscientist Patrik Brundin was twelve years old when his father was diagnosed with PD. He resolved to devote his life to finding a cure for the disease and elected to study medicine at Lund University in Sweden. In the late 1990s, he joined Anders Bjà ¶rklund, a pioneer of neural transplantation, to work on a series of neural grafts aimed at reversing the symptoms of PD. A neural graft is an experimental procedure for transplanting neural tissue into the brain. The operations were controversial because the transplanted neural tissue came from aborted fetuses. Research had shown that the optimal time to transplant human fetal-brain tissue from the substantia nigra was from six to eight weeks after fertilization. Because only 10 percent of the fetal cells are likely to survive the entire procedure, the neurosurgeon may need to implant cells from multiple fetuses in one operation. To prepare for the operation, the fetal tissue has to be dissected under the microscope so that only those cells whose destiny is to make dopamine would be transplanted. Attached to the substantia nigra tissue are cells that have different fates to become cartilage, skin, etc. If the surgeon isnt careful and grafts these cells into the brain, theyd grow into big bits of skin and cartilage. It is a delicate process. The entire fetus is only the size of a fingernail; the substantia nigra, the size of a pin. After hours of painstaking dissection, the fetal cells will be mixed with a chemical called trypsin to dissociate the cells into a liquid suspension. Researches with rats had shown that fetal cells grafted in the substantia nigra did not reverse PD-like symptoms, because the grafted nerve fibers could not grow long enough to reach their targets in the striatum. So the neurosurgeon will implant the fetal cells in the striatum. In the 1990s, 18 cases of neural grafting operations were conducted at Lund, and over 300 worldwide, with encouraging results. By 1999, many people believed this method is the only way to cure PD. But for others, the results were uncontrolled trials with a potential for a placebo effect. This led two teams in the United States to propose controlled blind trials of fetal tissue transplantation operations. Patients entering the trial would be assigned to one of two groups: a treatment group and a control group. Patients would not know which group they were in and would continue taking their regular dopaminergic medication. The first study performed the trial separately for people over and under sixty. The doctors held follow-up meetings with the patients for twelve months. In 2001, the team reported the results. The over-sixty treatment group experienced no measurable improvement compared to the control group. The under-sixty treatment group got some improvements, but the researchers found worrying evidence of adverse side effects: facial dystonias and dyskinesias. Unlike L-dopa-induced dyskinesias, which disappear as patients medication wears off, these dyskinesias were coming from the graft, and they were permanent. The second study assigned the patients randomly to two treatment groups one using material from a single fetus, the other using material from four fetuses and a control group. The groups were followed for two years and tested using UPDRS. There was no difference between the three groups, showing that fetal dose didnt matter, and again some patients developed graft-related dyskinesias. These two studies killed the field of neural transplantation. A decade after these studies, Brundin is still a strong supporter of neural grafting. He claims the studies had numerous flaws. Brundin may be correct about neural graftings efficacy. It worked in the cases of two patients in the Lund series. The two patients were diagnosed thirty years ago. Both responded well to L-dopa, but developed severe L-dopa-induced motor complications. In the 1990s, they went to Lund, where the surgeons transplanted dopaminergic fetal tissue into the striatum on both sides of their brains. After four years, both patients could drop all dopaminergic mediations. Their PET scans showed clear signs of new dopamine production in the striatum, and their motor states, as measured by the UPDRS, showed a sustained benefit. These cases showed that this bold strategy can work and serve as a caution against dismissing neural grafts prematurely. The early scientific trials of levodopa failed. But scientists like George Cotzias persisted and worked out the correct dosing regimen, and the failure turned into spectacular success. In Europe, a large trial called TRANSEURO is under way involving some 150 patients. The work might redeem neural grafting. In the last few years, a potential alternative to fetal cells and embryonic stem cells has become available. In 2006, Japanese researcher Shinya Yamanaka showed in mice that ordinary skin cells could be reprogrammed to become pluripotent capable of becoming any cell. Soon after, Yamanakas technique was achieved with human skin cells. Rather than using fetal cells, researchers can take a patients own skin cells, reprogram them to become so-called induced pluripotent stem cells (iPSCs), then let them develop into dopamine neurons. These neurons can be studied in the lab or grown for neural grafts. Such iPSCs not only bypass the ethical issues plaguing embryonic stem cells, but also have other advantages. Because iPSCs are derived from the patients own cells, there is no need for immunosuppressive drugs. But because there is a risk that such cells might turn cancerous, it may take decades to develop a safe and effective procedure. Key Takeaways In the late 1990s, Patrik Brundin worked on a series of neural grafts aimed at reversing the symptoms of PD. Two controlled blind trials of fetal tissue transplantation operations conducted in the United States in early 2000s showed that the treatment group experience no measurable improvement compared to the control group. It was also worrisome that some patients developed graft-related dyskinesias. In 2006, Shinya Yamanaka showed that ordinary skin cells could be reprogrammed to become pluripotent.

Myopia Development in Infants :: Vision Sight Nearsightedness Disorders Essays

Myopia Development in Infants An impairment in vision can lead to a very challenging life. Many Americans suffer from abnormalities in their vision. They suffer with diseases such as glaucoma, hyperopia, and myopia. Myopia, or nearsightedness, is fairly prevalent in the United States of America. In fact, it is estimated that twenty-five percent of the population of the United States is nearsighted (Kolata, 1985). Myopia occurs when the resting eye becomes focused on distant objects. The lens of the eye must become thicker and the radius of curvature must be increased in order for the eye to look at nearby objects. In individuals with myopia, the eyes are excessively long. This causes the image to form in front of the retina as opposed to on it (Kolata, 1985). Myopia frequently results from excessive postnatal eye growth. Typically, it develops in the early school years; however, some cases do not develop until early adulthood (Quinn, Shin, Maguire, & Stone, 1999). Myopia is a very serious disease that can have a tremendous effect on the life of a child. Approximately 5.6% of blindness among American school children can be attributed to myopia. Furthermore, it predisposes individuals to retinal detachment, retinal degeneration, and glaucoma (Quinn et. al., 1999). The cause of myopia has not yet been determined. However, children of parents with myopia tend to develop myopia more frequently than children with nonmyopic parents (Young et.al., 1998a). The two highest factors that contribute to myopia are myopic parents and doing "near work". Other indications for the development of myopia include childhood illnesses, low birth weight, and nearsighted siblings (Review of Optometry, 1999). Since a definite cause for myopia has not been determined, researches are divided as to whether the disease is caused by genetic factors or environmental factors. The debate for the genetic theory begins with the thought that myopia may be due to a dominant gene that is inherited by the child from the parent (Young et.al., 1998a). There is evidence to suggest that genetic heterogeneity attributes to high myopia ( Young et.al., 1998b). This implies that the child who inherits diversified genes from his or her parents is more likely to develop myopia. However, it is also thought that myopia may be caused by influences from the nervous system that are not normal and have a negative impact on the developing eye. Thus, it may, as well, be genetically determined (Kolata, 1985). The basis for the genetic theory is supported by the fact that myopia tends to run in families.

Nokia Strategic Management

Nokia’s Strategic Management Nokia Description of Company Nokia envisions a world where connecting people to what matters empowers them the most of every moment Nokia's CEO Olli-Pekka Kallasvuo Generation of Nokia NOKIA’S FIRST CENTURY: 1865-1967 †¢ The first Nokia century began with Fredrik Idestam's paper mill on the banks of the Nokianvirta river. Between 1865 and 1967, the company would become a major industrial force; but it took a merger with a cable company and a rubber firm to set the new Nokia Corporation on the path to electronics. Generation of Nokia THE MOVE TO MOBILE: 1968-1991 †¢ The newly formed Nokia Corporation was ideally positioned for a pioneering role in the early evolution of mobile communications. As European telecommunications markets were deregulated and mobile networks became global, Nokia led the way with some iconic products. Generation of Nokia MOBILE REVOLUTION: 1992-1999 †¢ As mobile phone use booms, Nokia makes the sector its core business. By the turn of the century, the company is the world leader. In 1992, Nokia decided to focus on its telecommunications business †¢ As adoption of the GSM standard grew, new CEO Jorma Ollila put Nokia at the head of the mobile telephone industry’s global boom – and made it the world leader before the end of the decade. Generation of Nokia NOKIA NOW: 2000-TODAY †¢ Nokia sells its billionth mobile phone as the third generation of mobile technology emerges. Nokia’s story continues with 3G, mobile multiplayer gaming, multimedia devices and a look to the future. Organizational Structure NAVTEQ:Manages digital map consumermobile device and marketing Nokia Siemens Network: Provides sales operational support to the units Services & Development Office. data thechannel,fixednavigation systems, Corporate Software: Develops Gives automotive network Markets: Provides supply chains, wireless and brand portfolio, Devices: Develops and manages for Internet services in 5 mobile navigation devices, messaging and games), applications, infrastructure, corporateof Internet-based mapping platforms to areas (music, maps, media,components. futureservice and worksandand andincludes communications and networks growth opportunities. activities. he sources strategic and explores government services an solutions. professional and business easily, accessible manner to consumers. deliver the services into operators and service providers. Vision of Nokia †¢ The full power of being connected †¢ Enable people to be wherever they want, whenever they want †¢ Life becomes more flexi ble and spontaneous †¢ Innovating, creating and sharing †¢ Technology becomes invisible †¢ Nokia never miss an opportunity to get the most out of life Goals of Nokia †¢ To become the leading provider of mobile solutions, because in the mobile converged internet space consumers expect seamlessly integrated solutions. To deliver these solutions requires continuous relationships with consumers and vibrant ecosystem. SWOT ANALYSIS STRENGTHS †¢Brand awareness †¢Technology leader in manufacturing mobiles †¢Market leader †¢Presence across 150 countries WEAKNESSES †¢Not good at software †¢Performance of Symbian OS is lackluster †¢Increasing dissatisfaction levels with its smartphone †¢Very weak market share in US OPPORTUNITIES †¢Huge loyal customer base †¢Huge presence in developing countries †¢Can use its infrastructure business (Nokia Siemens Network) to educe the bargaining power of mobile THREATS †¢Rapidly c hanging industry †¢Changes of missing Inflection point is high †¢Threat of entry from new business (Nokia Siemens players, Microsoft might Network) to reduce the enter smartphones market. bargaining power of mobile Google has just entered the operators market with Nexus One. Strategy Formulation Product Differentiation ? Applications are the product differentiator ? Nokia’s OVI Store ? Projection: in 2014 6. 67 billion applications would be downloaded ? Increase User Satisfaction Index ? Alliance with software developers ? Increase community strength of Maemo Strategic Objectives †¢ Irresistible solutions and vibrant ecosystems †¢ Direct and continuous consumer relationships. †¢ Best devices – Broadening their geographic reach – Broadening their device base will grow their service business †¢ Smart services – Creating relevant and personalized services – Target: 300 million people using their smart services by 2012 Strategy Formulation Cost Differentiation †¢ Nokia can set an industry enchmark for operating profits †¢ Pressure on competitors †¢ Cost leadership an invincible position against competitors †¢ Fight head-on with Apple Strategies of Nokia †¢ Competitive environment is changing †¢ Consumer needs are changing †¢ The nature of consumers’ relationships with companies is changing †¢ Irresistible solutions & vibrant ecosystem †¢ Transforming into a solutions driven company optimizing user experience. †¢ Laying the foundation for an inclusive and sustainable ecosystem †¢ Direct and continuous consumer relationships †¢ Best devices †¢ Smart services Strategies Evolution of Nokia Competitive Strategy NOKIA NOKIA Broad differentiation strategy Mass Market Low cost mass market strategy Niche Market Low cost niche market strategy Focus differentiation strategy Functional Strategy †¢ Reduce product portfolio †¢ Opportunity for targeting information users †¢ Target specific customers and specific lifestyles †¢ Connect emotionally with the target †¢ Define roadmap of Operating Systems (Symbian or Maemo) Corporate Strategy †¢ Continue divestments †¢ Concentrate resources and energy in smartphone business

Toothpaste critique

What's in This Toothpaste? By David Botanist. The audience/reader Is informed about how toothpaste In made, the Ingredients which are used to make Just a bottle of tube and other alternatives that can be used if you opinion about toothpaste changes. The author talks about if toothpaste is something you should consider or keep using. There are a few examples of diction which are present in the essay, the first one would be, â€Å"It's there because people like to have a big gob of toothpaste to spread on the brush.This creates a mental picture/image in the readers mind because, this effect relates to Imagery while the reader Is reading that passage they can relate to It because they have seen It in first person. Another example of imagery is present as the author states, â€Å"The tube of toothpaste is squeezed, it's pinched metal seams are splayed. † This creates the same visual effect in the readers mind, when they are doing that and it is impossible to make the toothpaste t o come out, so this relates to the readers past experience.Another example where David Botanist shows imagery is, â€Å"This is the flavoring, and it has to be strong. Double rectified peppermint OLL Is used. † This creates an Imagery of smell which the reader often smells after brushing his/her teeth. In the essay syntax Is present, the first example is where and how the author places his paragraphs, the author in depth states his first topic and first ingredient and then backs up his argument, he then explains what the ingredient is used for and also gives a description.This show that the paragraphs are well placed and explained, this creates an effect of keeping the essay neat and well organized. Another example where the author shows sentence structure Is how the author keeps the paragraphs hurt, which tends to trick the reader that he Is reading less but really he Is reading the same but faster. This creates an effect of speeding up the tempo of the essay. Usually if the paragraphs are too long the reader tends to get bored or distracted.Another example is the author makes a statement, â€Å"Water mostly, 30 to 45 percent in most brands: ordinary, everyday simple tap water. † In the essay this is an incomplete sentence where the author makes a statement and carries on, this creates an effect of a pause so the reader can think about that basically people pay three dollars or more for water. A powerful rhetorical device which is used is juxtaposition, where the author compares two things, toothpaste and water, â€Å"studies show that brushing with just plain water will often do as a good Job. This give an alternative for the reader if their opinion on toothpaste changes. A second rhetorical device is hypoxia, where the author raises a question but ends up answering it himself to add effect, â€Å"Is that it? Chalk, water, paint, seaweed, antifreeze, paraffin 011, detergent, and peppermint? Prove his point, also it allows the author to write more, the effect of this is that this is play on word.The third rhetorical device which is present is colloquialism, word like â€Å"bobbing,† â€Å"gob,† â€Å"goodies,† and other slang words that the author uses to get his point across for everyone, interpreting the author you can tell that the author uses informal words to connect with the younger audience. The tone that the author sets is for a younger audience, the author uses in formal word, to target teenagers, another target is the people who don't know much about toothpaste. The title of the essay grabs the attention of the reader and forces them to read. Toothpaste is meeting people use daily but they have no clue what it is made up of.The mood which is created is the audience feeling disgusted because toothpaste manufactures use; pesticide, detergent and chalk: the kind that teachers use to write on the black board, and that is the same toothpaste we put in our mouth. Another mood is the audience is i nformed about how bad toothpaste could be if swallowed. Overall the writing choices made by the author were remarkable, really loved the message the author way trying to get across. In the end David Botanist serves his purpose of writing the essay of educating people about toothpaste.